Welcome to the #BloodandBone community Job Board. If you have an opening in your lab that you would like to post here, please contact us.
(Disclaimer: please note that all postings will have the date that they were brought to our attention and that calls may have closed without our knowledge)
December 12th, 2021
A postdoctoral position is available immediately in the platelet laboratory of Jeffrey S. Berger, MD, MS, at NYU Langone Health’s Leon H. Charney Division of Cardiology. Our laboratory is dedicated to elucidating the mechanism and regulation of platelet mediated complications, in atherogenesis, thrombosis and inflammatory diseases.
Platelets are key players in the fields of thrombosis & hemostasis, inflammation and immune activation. Using a combination of human studies, mouse models, and cell culture, we investigate novel signaling pathways in platelets that contribute to cardiovascular risk and other inflammatory diseases. The successful candidate will investigate novel and targetable signaling pathways in platelets. The postdoc joins a dedicated and hardworking team determined to reach results that change the way we treat cardiovascular disease and inflammatory diseases (J Am Coll Cardiol 2018;71:53-65; Science Translational Medicine 2019; Sci Adv. 2021 Sep 10).
The ideal candidate holds a PhD and/or an MD in biological sciences or biomedical-related fields. Candidates must have a solid background in one or more of the following fields: thrombosis and hemostasis, immunology, and/or genetics. We are looking for a creative and driven individual with a strong publication record, ideally with expertise in platelet physiology, cardiovascular research, molecular biology, flow cytometry, and/or cellular imaging/microscopy. Previous experience in high throughput sequencing (e.g. RNA-seq, ATAC-seq) is highly desired. Applicants with murine and animal microsurgery experience are encouraged to apply.
To apply or to obtain more information about the position, please contact Dr. Berger at jeffrey.berger@nyumc.org. Applicants should include a CV, brief statement of research background, and the names of three references.
July 15th, 2021
The Alachkar Lab at the USC School of Pharmacy, Titus Family Department of Clinical Pharmacy is seeking a Postdoctoral Scholar – Research Associate to join our ongoing studies on cancer genomics and Therapeutics. Recent Ph.D. graduates with a successful publication record in scholarly journals are encouraged to apply. We are translational genomics and experimental therapeutics lab that focuses on identifying and investigating novel therapeutic targets in acute myeloid leukemia (AML) and developing new therapeutic strategies. Our lab is also interested in characterizing the immune repertoire of patients with AML using TCRseq analysis to be leveraged in the development of novel neoantigen prediction algorithms that can then be validated in cellular and animal models. We seek a highly motivated scientist proficient in using routine molecular biology techniques for genomics/epigenomic studies. Hands-on experience with high throughput assays and next-generation sequencing-based platforms is required. In addition, the candidate should have a strong background in cancer biology, immunology and computational biology, bioinformatics, or biostatistics. Computational skills, including experience with bioinformatic tools and packages, are needed. Experience with data mining, especially for ‘omics’ datasets, or developing pipelines/software for large biological datasets is desired.
Responsibilities include a) Immune profiling of clinical samples, b) Conducting cellular, molecular, and in vivo experiments for hypothesis-driven research, c) Performing computational and bioinformatic analyses; and d) Preparing presentations and publishing scientific manuscripts under the direction of the Principal Investigator. The applicant must have excellent organizational and communication skills. The individual should have experience with working in teams, as well as the ability to work independently. The postdoctoral trainees will be encouraged to submit their own fellowship and grant applications. The candidate will enjoy a highly collaborative environment as a part of the USC research community.
Interested candidates should send a CV to Dr. Alachkar (alachkar@usc.edu), Assistant professor, USC School of Pharmacy.
Salary and benefits commensurate with experience and NIH guidelines.
Applicants should attach the following:
1) Statement of research interests and career goals
2) Curriculum Vitae including bibliography
3) Names and contact information for three references
Minimum Education: Ph.D.
February 11th 2021
Postdoctoral Fellow – Laboratory of Roy L. Silverstein (Interim Director and Senior Investigator, Versiti Blood Research Institute; and John and Linda Mellowes Professor and Chairman, Department of Medicine, Medical College of Wisconsin
We are seeking highly self-motivated candidates for a Postdoctoral Fellow position in the Versiti Blood Research Institute (BRI) in the laboratory of Dr. Silverstein, the former President of the American Society of Hematology (ASH) and a leading investigator in the fields of thrombosis and vascular biology. His lab work focuses on a specific cellular receptor known as CD36, the defining member of the Type 2 scavenger receptor family, that is expressed on the surface of platelets, macrophages, and adipocytes. The lab has developed a “tool kit” to study this protein in vivo and in vitro, including genetic knockout mice crossed into several disease model backgrounds, specific antibodies and shRNA reagents, and highly specific ligands. The fellow will work on an NIH-funded collaborative project with the lab of Dr. Weiguo Cui seeking to understand how CD36 signaling impacts mitochondrial function during atherosclerosis.
Qualified applicants (0-4 years of postdoctoral training with either PhD or MD degree) must have strong knowledge and research experience in biochemistry, cell biology, and immunology. Applicants must be able to work independently and have excellent written and oral communication skills in English. The successful applicant will be eligible to apply for the prestigious BRI Director’s Award which provides an additional supplement to the standard stipend.
Located on the campus of the Milwaukee Regional Medical Center, adjacent to the Medical College of Wisconsin, the Blood Research Institute offers a dynamic multi-disciplinary research environment with access to state-of-the-art facilities and a training environment for career development. https://authoring.versiti.org/research/blood-research-institute.
Applicants should send their CV with email address to: Dr. Yiliang Chen (yilchen@mcw.edu)
February 3rd 2021
Senior Scientist – Genetic Engineering
STRM.BIO
Full-Time Position (Cambridge, MA)
The Company: STRM.BIO (pronounced “storm bio”) is a pre-clinical, VC-backed biotechnology company that is leveraging naturally-derived extracellular vesicles (EVs) to deliver gene therapies in vivo. We believe in a culture where people come first and that personal accountability is key to a healthy organization. We believe that there is both elegance and efficiency in simplicity, and we let this approach drive both our science and our strategy.
We are assembling a team of leaders who share our company values, who believe in the promise of EVs to bring transformative therapies to patients, and who will actively contribute to a culture of continuous learning, innovative discovery, and unyielding commitment to high quality science.
The Technology: STRM.BIO is creating a proprietary EV platform to deliver gene therapies in vivo and establish a new class of therapeutics. EVs are natural carriers of nucleic acids and proteins and hold tremendous promise as direct cell messengers for gene therapies due to their innate targeting, amenability to large scale/commercial manufacture, and low immunogenicity. At STRM, we are aiming to create new therapies and uniquely enable effective targeting of existing ones to democratize gene therapy. We are just beginning to explore the potential impact of our platform and are looking to recruit team members who can help us bring this larger vision to light.
The Person: The Senior Scientist position is full-time and will be predominantly remote, but you should be prepared to conduct in-person benchwork as needed. You will work directly with the STRM Director of Research to manage your scientific programs while providing critical scientific leadership and genetic engineering guidance. You should be very comfortable with coordination of multiple external academic and/or contract research groups, as this will be central to your management role.
To be successful in this role, you should be someone who is always up for a challenge and finds the unique demands of the fast-paced startup environment motivating. You will need to be adept at managing both projects and people, and be able to do both while espousing the people-first, simplicity-oriented values we hold as core to STRM culture.
To learn more about this position, please submit your resume and cover letter directly to Dr. Jonathan Thon, CEO at careers@strm.bio
January 16th 2021
Jeff Molkentin: TENURED TRACK FACULTY POSITIONS IN MOLECULAR CARDIOVASCULAR BIOLOGY (Assistant, Associate or Full Professor)
Cincinnati Children’s invites outstanding candidates to apply for tenure-track positions to join the Heart Institute in the Department of Pediatrics at the University of Cincinnati. The applicant shouldhave a PhD and/or MD with a research program that investigates the molecular biology of cardiac muscle or skeletal muscle. The successful applicant will join a multi-disciplinary world-renowned faculty performing cutting edge heart and skeletal muscle research with a strong emphasis on disease mechanisms.
Our existing faculty members are world-renowned researchers in developmental cardiac biology, pediatric and adult disease-based heart research, and skeletal muscle and muscular dystrophy biology, fibroblast biology and transcriptional regulatory mechanisms, which complements one of the strongest pediatric clinical heart programs in the country for translational research endeavors. To learn more check out our website at:
https://www.cincinnatichildrens.org/research/divisions/m/mcb
The research Institute at Cincinnati Children’s attracts over $250 million in annual external grant support, with approximately 1.4 million sq ft of research space, most of which was recently built. We also have some of the best core support infrastructure for a research institute anywhere in the USA.
The successful applicant would be appointed within the Division of Molecular Cardiovascular Biology ofthe Heart Institute, headed by Jeffery D. Molkentin PhD.A letter of interest, accompanied by a complete curriculum vitae should be electronically sent to:
Jeff.molkentin@cchmc.org
October 28th, 2020
Anandi Krishnan: Hi y’all. Posting here for a postdoctoral or a staff scientist opening to join my developing research program at Stanford:
NIH-funded Instructor/Junior Faculty at the Department of Pathology, Stanford School of Medicine is seeking a motivated postdoctoral fellow or staff scientist with curiosity toward platelet and megakaryocyte biology, and expertise in molecular biology and cell signaling. Overall objective of the research is to uncover cross-functional roles of platelets (and parent megakaryocytes) in disease settings beyond their classical role in hemostasis and thrombosis (e.g. cancer, inflammation, infection). Research strategies include integrating multi-omics discovery with molecular, cellular and in vivo approaches. Immediate research goals are in mechanistic characterization as well as clinical laboratory validation of substantial platelet transcriptomic signatures derived from a large cohort of patients with hematological disorders.
Projects are collaborative across senior faculty at Stanford and external institutions.
Ideal candidate is one who is highly motivated, has a strong interest in basic/translational research, and is committed toward the development of a research program. Attentive and personal mentorship is assured.
A background in hematology, cancer cell biology or immunology is preferred but not required.
Initial appointment is for one year with the possibility of renewal based on satisfactory performance and continued funding.
To apply, please send a detailed CV to anandi.krishnan@stanford.edu with ‘Platelet Research Interest’ included in the email subject line.
October 14th, 2020
Neil Morgan: We have an exciting opportunity for an experienced post doc to join @neilvmorgan grp @bhamplateletgrp @icvs_uob – An NIH-funded position for 3.5 years to work on an exciting project / unravelling the mechanism of a novel protein slfn14 and its role in haemostasis and thrombosis. https://www.jobs.ac.uk/job/CBU550/research-fellow. Please email n.v.morgan@bham.ac.uk if interested.
October 7, 2020
The Nichols Lab (www.stjuderesearch.org/site/lab/nichols) at St. Jude Children’s Research Hospital is seeking a Research Laboratory Specialist (staff position) or Postdoctoral Fellow to conduct research in the field of cancer predisposition using in vitro and in vivo models of hematopoiesis and leukemia.
Nichols lab is interested in identifying novel genes and genetic variants that contribute to development of cancer and primary immunodeficiency. We are using human and mouse models to decipher how these germline variants impact hematopoiesis and promote leukemogenesis. We are characterizing the hematopoietic phenotypes of these animals and examining the underlying transcriptional mechanisms. To model these cell compartments and perform assays in vitro, we also employ a number of cell lines including murine-derived HSPCs and pro-B cells, as well as human iPSCs. Ultimately, our goal is to better understand how germline and somatic genetic events perturb key cellular and molecular pathways that then lead to leukemia.
We are currently seeking a Research Laboratory Specialist (staff position) or Postdoctoral Fellow who has experience working with mice, such as breeding, genotyping, harvesting organs, completing flow cytometry, and carrying out retroviral or lentiviral transduction of bone marrow cells followed by adoptive transfer. A background in hematopoiesis or leukemia modeling is desired, but not necessary. We are also interested in candidates who have interest and experience in handling and differentiating iPSC or a background in functional genomics, such as carrying out large scale mutagenesis assays. To apply, please send a detailed CV to Kim Nichols, MD (kim.nichols@stjude.org).
September 29, 2020
David Bark: We have a Staff Scientist position open in my group on an NSF-funded platelet mechanobiology project. We have an invigorating multidisciplinary environment based out of the Washington University School of Medicine Department of Pediatrics, Division of Hematology and Oncology. This project will involve the investigation of how platelets produce and respond to mechanical forces in complex flow environments. We seek individuals with an interest in actomyosin machinery of the cell and in utilizing and/or developing biophysical tools to probe platelets. Our lab has ongoing projects in studying flow-dependent effects on blood, heterotypic cellular interactions, the role of mechanics in cardiovascular development, and the development of blood-contacting medical devices. After recently moving, we’re also hiring a postdoctoral fellow and research technician. Please contact me, Dave (bark@wustl.edu), if interested. The job ID is 48732 https://hr.wustl.edu/careers/
September 16, 2020
The Agarwal Lab at the OHSU Knight Cancer Institute is looking for a motivated postdoctoral fellow or an Assistant staff scientist.
Our laboratory focuses on identifying novel intrinsic- and extrinsic signaling pathways that are requisite for leukemia progression, clonal evolution, and drug resistance. The work will concentrate on the discovery and validation of new therapeutic targets in hematologic malignancies and the molecular characterization of signaling pathways involved in disease pathogenesis. The position is in an interdisciplinary, collaborative, and highly translational environment in the OHSU Knight Cancer Institute and the Department of Hematology and Oncology in the OHSU School of Medicine. Highly-motivated candidates with expertise in molecular biology, hematopoiesis, cell signaling/ epigenetics, and in vivo models who are interested in a career in oncology basic/translational research will be most competitive for this position. The individual should have demonstrated distinguished record of scientific accomplishments. Interested candidates reach out to me directly at agarwala@ohsu.edu
September 14th 2020
Platelet society: In a recent early career researcher (ECR/trainee) survey, we asked you what you wanted from the Platelet Society. 60% of respondents said that they would like to see additional activities from the society. Activities that people would like to see include:
- announcements/notice board/blog
- Webinars
- Mentoring/career development opportunities
- Socials
- Skills repository
In response to this Carly Kempster and Kirk Taylor are launching an ECR Working Group to implement new initiatives to deliver on your feedback.
The working group will consist of six people and will be tasked with developing three projects.
- Mentoring and professional development
- Engaging with members
- Knowledge transfer
More information can be found here. The group will be supported by The Platelet Society Executive Committee. Please contact Carly or Kirk if you would like any additional information or discuss the roles informally. We are keen to reflect the diversity of the society and applications are open to all ECRs. Please do encourage your colleagues and peers to apply.
Applications are open through September (closing 30/09/20) and appointments confirmed in October.
August 17th, 2020
Alisa Wolberg: An NIH-funded postdoctoral position is available in Dr. Alisa Wolberg’s Lab (https://www.med.unc.edu/wolberglab/) in the UNC at Chapel Hill Department of Pathology and Laboratory Medicine and UNC Blood Research Center. We use in vivo and in vitro models to investigate coagulation mechanisms in health and disease. Our lab emphasizes a culture of diversity, responsibility, independence and collaboration, and shared excitement for scientific discovery. Ongoing projects focus on arterial and venous thrombosis, hormone-induced thrombosis, hemophilia, and cancer. A link to Alisa’s recent #BloodandBones webinar summarizing some of our recent work is: https://www.dropbox.com/s/egztb9t67zoc054/Wolberg_BloodBones.mp4?dl=0. For the new postdoc position, we especially seek individuals interested in pulmonary embolism, cell biology of coagulation factor production, and/or the intersection of procoagulant and fibrinolytic mechanisms in obesity and cancer. Please see https://unc.peopleadmin.com/postings/182629 and contact Alisa (alisa_wolberg@med.unc.edu) for more information.
August 10th 2020
A. Valance Washington: Post-doctoral fellowship. We are offering a unique opportunity for growth and development. Our lab is located at the University of Puerto Rico and we have state of the art facilities housed in a new molecular science building. Our lab studies the immune-hemostatic interface and focuses on visualizing platelet-leukocyte interactions in the vasculature. While the lung is our primary target, we would like to also develop the ability to visualize these interactions and their effects in other key tissues such as in the liver, spleen, and tumors. We have a funded position to study platelet function in acute respiratory distress syndrome (focused on SARS-CoV-2), novel platelet/fibrinogen interactions and/or platelets in cardiovascular disease. Interested parties please send your CV to: anthony.washington@upr.edu
August 5th 2020
Nick van Gastel: POST-DOCTORAL POSITION in Leukemia Biology / Tumor microenvironment Our research group is part of the de Duve Institute, a multi-disciplinary and international biomedical research institute of the UCLouvain in Brussels. Our goal is to uncover how normal and malignant hematopoietic cells communicate with the bone marrow microenvironment. We focus particularly on the role of nutrients and cell metabolism, using state-of-the-art metabolic analysis techniques in combination with mouse models and cell (co-)culture systems to unravel the metabolic communication between hematopoietic/leukemic cells, stromal cells and immune cells in the bone marrow niche.
Your mission: We are looking for an ambitious candidate to pursue an exciting post-doc project in our lab, aiming at understanding how metabolic crosstalk between leukemia cells, immune cells and stromal cells drives development of chemotherapy resistance.
Your qualifications and skills: The candidate holds a PhD in Biomedical Sciences, Molecular/Cellular Biology,Biochemistry or equivalent. A background in cancer cell biology, hematology or immunology is preferred but not required. Experience in working with mice is recommended. The candidate is highly motivated, quality-oriented, has a strong interest for biomedicine and fundamental research, and is ready to commit for a challenging project. A good command of English (spoken and written), good communication skills, and ability to design, perform and analyze experiments independently as well as in a team are necessary. Mentoring of 1 to 2 students (PhD or undergraduates) is likely to be required during the project.
Specific requirements: The candidate is considered in “international mobility”, i.e. they have not resided, studied or worked in Belgium for more than 24 months over the past 3 years before the start of the post-doc.
What we offer: A two-year postdoc fellowship, potentially renewable. Candidates are encouraged to apply for their own fellowship during the first year, if possible.You will join a young and dynamic team, and have the opportunity to work on high impact projects in a multidisciplinary environment with excellent training conditions. We aspire to create a lab culture where all feel welcome,regardless of age, race, gender or cultural background.
Interested? Applications will be processed in accordance with the rules of personal data protection (more about our privacy policy: https://www.deduveinstitute.be/privacy-policy).
Please send your application to Prof. Nick van Gastel at nick.vangastel@uclouvain.beThe application should include: 1) a CV including previous researchexperience and publications; 2) a short cover letter (max. half a page)describing the candidate’s motivation, career objectives, research interests,expertise; 3) the name, affiliation and contact information of two references.For more information about our research: https://www.deduveinstitute.be/cellular-metabolism-and-microenvironment
Susanna Fustolo-Gunnink: HEMOCURE: Improving neonatal platelet transfusions – two PhD positions for clinical and fundamental projects.
Are you interested in pursuing a PhD in neonatal platelet transfusion research? Do you aspire to perform clinical research, but do you also have affinity for fundamental research? Or do you want to do a fundamental PhD but do you also have affinity for clinical research? Then consider applying for this unique twin PhD project!
Project
Babies that are born prematurely often receive platelet transfusions to prevent bleeding when their platelet count drops below a certain threshold. A recent clinical trial unexpectedly showed that babies who were transfused liberally (at a higher threshold) had worse outcomes than babies who were transfused restrictively (at a lower threshold). In this research project we will gain fundamental insight into the function and activation pathways of adult and neonatal platelets and investigate why platelet transfusions can lead to adverse effects in premature babies and how we can improve our transfusion guidelines for this vulnerable population.
Two PhD students will work closely together in this project, one with a focus on fundamental research and one with a focus on clinical research. You will work closely together in all stages of the project and will be supervised by an interdisciplinary group of researchers including fundamental researchers, neonatologists, clinical epidemiologists and data scientists. As fundamental PhD student, you will use mass spectrometry-based proteomics to get a full understanding on the function and activation of blood platelets, investigate developmental hemostasis in premature babies, and you will investigate the effects of platelet transfusions on hemostasis in premature babies with and without bleeding. As clinical PhD student, you will implement an existing prediction model for bleeding into the electronic patient systems in neonatal intensive care units in the Netherlands. You will then use the data generated from this system to further develop and improve this model. You will be responsible for obtaining the blood samples needed for the fundamental assays, and will obtain the relevant clinical data to interpret these assays.
July 13th 2020
Dianne van der Wal: We are looking for various students: Summer, Master’s and/or Honour’s students in Sydney, Australia
Project 1: The effect of aspirin intake on platelet quality following storage
Platelets, crucial for cessation of bleeding, deteriorate rapidly during storage, leading to a short 5-day shelf-life. At a donor centre, donors are only able to donate platelets when they have not have taken aspirin or other anti-inflammatory medications (Nonsteroidal Anti-inflammatory Drugs, ‘NSAID’ including ibuprofen and naproxen) 7 or 3 days respectively prior to donation since these drugs have a negative impact on platelet function. At blood centres, due to a shortage of platelets, these guidelines might be relieved in the future to increase the platelet pool in order to meet the increasing demand.
In the laboratory, it is known that addition of aspirin affects platelet function, potentially leading to their death (van der Wal DE, JTH, 2010). However, what the effect is on platelet product quality and following storage is currently unknown (Driver B et al, RPTH, 2020). In this project, we will study the effects of aspirin and other NSAIDs.
These findings may allow blood centres to develop new guidelines for aspirin/NSAID deferral in the blood centres. Also, this potentially leads to platelet products that store well or better under standard blood banking conditions.
Project 2: The role of deglycosylation in platelet function and during storage
Platelets donated by some donors at the Blood donor centres do not store as well as others, leading to reduced survival and clinical effectiveness following transfusion into patients.
The platelet membrane is covered with complex, highly branched carbohydrates, which can be cleaved off by specific enzymes (e.g. neuraminidases). Although it has been shown earlier that deglycosylation triggers platelet apoptosis and clearance in an immune bleeding disorder (Li J/van der Wal DE, Nat Comms 2015). Neuraminidases are shown to be present in platelets and have an unexptected role in their function (van der Wal DE, Haematologica, 2020).
These findings may allow the Blood Service to develop a new way to possibly select the right donor for the right platelet product for different patient groups. This may also predict which donors are best suited to providing platelet products that store well under standard blood banking conditions.
You will be learning flow cytometry and various in vitro platelet function techniques.
Student attributes: Passion for (translational) research, willingness to learn new techniques, interest in biochemistry.
If you are interested, please contact Dr Dianne van der Wal: divanderwal@redblood.org.au for more information or check out:
https://www.donateblood.com.au/research/meet-the-investigators/dr-dianne-e-van-der-wal
Twitter: @DianvanderwalDr
July 9th 2020
Anirban Sen Gupta: The laboratory of Dr. Anirban Sen Gupta at Case Western Reserve University is seeking multiple post-doctoral candidates who may be interested in translational biomedical areas of hemostasis, thrombosis, thromboinflammation, and wound healing. Dr. Sen Gupta is a Professor of Biomedical Engineering at Case Western Reserve University, with secondary appointments in Department of Pathology and Department of Pharmacology at Case School of Medicine. Dr. Sen Gupta is also a co-founder and Chief Scientific Adviser for a biotechnology start-up company, Haima Therapeutics, focused on bioinspired technologies for the treatment of bleeding complications. The research in the Sen Gupta laboratory spans the areas of biomaterials, nanomaterials, microfluidics, microsensors and drug delivery, with applications across trauma, hematologic diseases, wound care, thrombosis/thromboinflammation, and point-of-care diagnostics. The laboratory has extensive collaborations between School of Engineering and School of Medicine at Case Western, as well as several active collaborations with the University of Pittsburgh, University of Michigan Ann Arbor, University of North Carolina Chapel Hill, University of Maryland, University of Colorado Denver and US Army Institute of Surgical Research San Antonio. Various research projects within the lab are supported by NSF, NIH and DoD. Details of past and current research projects in the laboratory are available at http://www.senguptalab.com. Research projects may involve, but are not limited to:
(1) Artificial blood surrogates: Bioinspired designs of blood surrogates including artificial platelets, artificial RBCs, co-formulation in plasma for whole blood surrogate design and evaluation using in vitro and in vivo models.
(2) Targeted drug delivery and nanomedicine: Nanomedicine systems for targeted applications in hemostasis, thrombosis, thromboinflammation and cancer.
(3) Microsensor design and evaluation: Surface-engineering of dielectric microsensors for the design of hand-held portable hematologic analyzers.
(4) Bioactive scaffolds and matrices: Hydrogels, tissue-adhesives and dressings for hemorrhage control, anti-infective coatings, wound care in trauma, burn, chronic wounds.
Successful candidates will have a recent Ph.D. in areas of biomaterials, platelet biology, coagulation, thrombosis/thromboinflammation, wound healing, and surface engineering. virology, microbiology, immunology, structural biology, or other related fields. Candidates with prior research experience in platelet biology, coagulation biology and in vivo models of bleeding/thrombosis/thromboinflammation are especially encouraged to apply. Interested applicants should send the following materials in an application packet, preferably as a single PDF file, by email to Dr. Anirban Sen Gupta (anirban.sengupta@case.edu): 1. Cover letter indicating current and future research interests 2. Expected starting date 3. Current location and visa status 4. Curriculum vitae 5. Brief summary of previous research experience (2-3 pages) 6. Names and contact information for 3 references
July 7th 2020
Lee Grimes: Postdoc positions available in the Grimes laboratory at Cincinnati Children’s Hospital, in Cincinnati Ohio (an affordable metro area of more than 2 million people, with access to the arts, great restaurants, excellent schools and parks).
Dual training in hematology/oncology and informatics (with Dr. Salomonis). The lab exploits cutting-edge omics tech to answer fundamental biological questions in hematopoiesis, marrow failure and myeloid leukemia. We develop new informatics tools when existing tools are insufficient to resolve the data. For example: PMID: 32494068, PMID: 30249787, PMID: 30243574, PMID: 29977015 and PMID: 27580035.
Cincinnati Children’s Hospital Medical Center (CCHMC) is an academic pediatric acute care children’s hospital with 634 pediatric beds which serves patients from 51 countries and 50 US states. CCHMC ranks third in 2019-2020 and 2020-2021 by US News and World Report, and receives the third-most NIH funds of any pediatric institution in the United States. CCHMC’s research mission is aided by a $3 billion endowment, which subsidizes state-of-the-art core facilities with career technicians for marrow transplant, single cell processing, flow cytometry, computational biology, etc. The training environment is especially rich for hematology/oncology research because of a robust and interactive research community.
Applicants must have completed a PhD in a related field, display critical and independent thinking skills, enthusiasm for science, and an ambition to succeed. Candidates should reach out to Dr. Grimes (lee.grimes@cchmc.org) with a curriculum vitae and reference contact details.
July 6th 2020
Robert Signer: The Signer Lab is hiring Postdocs! Our curious and creative team at UCSD investigates how the proteostasis network is uniquely configured to promote stem cell function and longevity, and encompasses new therapeutic targets in cancer. Learn more at signerlab.com!
Kate MacNamara: Postdoctoral Position in the MacNamara Lab
Albany Medical College, Center for Immunology and Microbial Disease
Join us! We are looking for a postdoctoral researcher to join our team. We study stress-induced hematopoiesis in murine models of infection and disease. Our goal is to better understand mechanisms regulating the impacts of inflammation on HSC function and hematopoiesis to mitigate HSC and bone marrow dysfunction. Looking for a curious, motivated, independent, and creative thinker who has strong communication skills. Experience in immunology, cell biology, microbiology, and/or stem cell biology, and experience working with murine models preferred. Expertise in flow cytometry, immunofluoresence, microscopy, and imaging is an advantage. Albany Medical College has a close relationship with the New York State Department of Health’s Wadsworth Laboratories, providing a diverse environment rich in infectious disease expertise. Albany is a mid-sized city within the upstate New York Capital Region, and has easy access to Boston, New York City, and the Adirondack and Berkshire Mountains!
Please apply by providing a cover letter (outlining your scientific interests) and your C.V. Please email the documents and any questions to: macnamk@amc.edu
https://www.amc.edu/Profiles/MacnamK.cfm
George Murphy: The Murphy laboratory (http://murphylaboratory.com) at the Center for Regenerative Medicine (CReM) at Boston University and Boston Medical Center has an opening for a highly motivated postdoctoral fellow in the field of stem cell biology and hematopoiesis. The postdoctoral fellow will join an interdisciplinary team to work on projects related to human hematopoietic stem cell (HSC) characterization, induced pluripotent stem cell (iPSC)-based disease modeling, and gene editing therapies for hereditary blood disorders. This position is immediately available, and is a great opportunity to further develop technical expertise and build a publication record for a career in cutting-edge research.
Duties and Responsibilities: Successful candidates will work independently, and as part of a team, to implement and coordinate ongoing research projects, as well as design and direct novel efforts to study hematopoietic disorders using ES (embryonic stem) cells and iPSC platforms. Applicants with technical expertise related to stem cell biology, viral gene transfer, and molecular biology are preferred.
Essential Qualifications: Applicants must have a Ph.D. in biological science (or closely related field) and relevant laboratory experience, including familiarity with tissue culture techniques.
Additional Qualifications: Successful candidates will be dedicated, creative, self-motivated critical thinkers with strong written and verbal communication skills. They will be expected to manage multiple detail-oriented tasks with minimal supervision and trouble-shoot as necessary.
Contact: Interested applicants should forward contact details and a current CV/resume to Dr. George J. Murphy at gjmurphy@bu.edu
Jeevisha Bajaj: We have postdoctoral positions available to study leukemia stem cell interactions with their microenvironment. The successful candidates will work on projects following up on our new genome-wide in vivo CRISPR screen identifying key new dependencies for aggressive myeloid cancers: https://www.nature.com/articles/s43018-020-0054-2
Our lab (https://www.urmc.rochester.edu/labs/bajaj.aspx) is a part of the Wilmot Cancer Center at the University of Rochester Medical Center, NY. This is a great opportunity to work in close collaboration with a fantastic group of scientists and clinicians at the Wilmot. Please contact me directly at Jeevisha_Bajaj@URMC.Rochester.edu
Ze Zheng: Interested in studying the mechanism of fibrinolysis, thrombosis and atherosclerosis? The laboratory of Dr. Ze Zheng at Versiti Blood Research Institute is seeking a postdoctoral research fellow with an interest in the organ cross talk between the liver and cardiovascular system through blood circulation in the context of cardiometabolic diseases.
Located on the campus of the Milwaukee Regional Medical Center, adjacent to the Medical College of Wisconsin, the Versiti Blood Research Institute offers a dynamic multi-disciplinary research environment with access to state-of-the-art facilities and a training environment for career development.
For more information or to apply for this position, please go to http://u.rfer.us/BCW.8i1JD, or send your cover letter and CV to Ze Zheng, MD, PhD, zzheng@versiti.edu.
July 4th 2020
Wally Whiteheart: The Whiteheart lab, at the University of Kentucky, USA, is looking for post-doctoral candidates with an interest in platelet “cell biology”. The lab focuses on platelet secretion mechanisms and function as well as platelet endocytosis and innate immune responses. Projects range from basic analyses of granule membrane fusion to clinical studies of HIV1/AIDS and lots in between.
Check us out at https://biochemistry.med.uky.edu/users/whitehe#profileTab1 or on Twitter at @LabWhiteheart and @SWWhiteheart. Contact whitehe@uky.edu if interested. (NIH and VA funded)
July 3rd 2020
Peter van Galen: The van Galen laboratory is recruiting a postdoctoral fellow to take on innovative research in the areas of blood development and leukemia. Applicants with computational and/or wet lab experience in any field of biology can apply. PhD degree is required at the job start date. See the following link for more details: https://www.dropbox.com/s/84frgiap5kioqvi/van%20Galen%20Postdoc%20ad.pdf?dl=0
July 2nd 2020
Matthew Flick: Postdoctoral Research Associate.
The Flick Lab (https://unclineberger.org/directory/matthew-flick/) at the University of North Carolina at Chapel Hill is looking for a Postdoctoral Research Associate interested in studying mechanisms linking coagulation factors to the progression and severity of pancreatic cancer. This is an NIH-funded project with established national and international collaborators. Those interested please check out the official university job posting at https://unc.peopleadmin.com/postings/181503.”
June 15th 2020
Anupriya Agarwal: OHSU Fellowship for Diversity in Research. Purpose and goals of the program:
The OHSU Fellowship for Diversity in Research (OFDIR) Program is a competitive program whose goal is to increase the diversity of the community of scholars devoted to academic scientific research at OHSU. We seek to attract promising researchers and educators from different backgrounds, races, ethnic groups, and other diverse populations whose life experience, research experience and employment background will contribute significantly to the academic mission of OHSU. Fellowships are available for postdoctoral training in all scientific areas of study at OHSU. Priority for fellowships will be given to individuals from historically underrepresented populations, U.S. citizens and/or permanent residents, and where there might be a research priority need. Successful candidates will receive mentored scholarly and research training as well as grant writing assistance to prepare them for a faculty position in a major university. Explore the tabs to the left to learn more about how to apply and to meet current and former OFDIR fellows. Read on below to learn more about the benefits of the OFDIR program.
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Benefits of the OFDIR program
Financial Benefits:
- Salary and benefits for first year of postdoctoral research (and support to seek other funding for additional years of research at OHSU)
- Funding of up to $5000 for professional development and research materials
- Funding of up to $3000 for relocation costs
Professional Development Benefits:
- Training workshops for grant- and manuscript-writing and one-on-one assistance (free of charge)
- Monthly professional development seminars (occasionally featuring guest speakers, lunch provided)
- Opportunities for networking, career development and other social events
Fellow Spotlight
This profile features one of our alumni fellows, Dr. Ginnifer Mastarone
June 9th 2020
Isabelle Becker: The Nieswandt lab at the University Hospital in Würzburg, Germany is looking for a PhD student and a Postdoctoral fellow. https://www.platelets.eu/
June 8th 2020
Keith Neeves: The Neeves lab at the University of Colorado Anschutz Medical Center in Denver is looking for a pre- and post-doctoral positions. We study the biophysical mechanisms that regulate blood clotting using in vivo, in vitro, and in silico models. A predoctoral position is available on identifying modifiers of genetic and acquired bleeding disorders. A postdoctoral position is available on measuring single platelet function relationships in microfluidic formats. Both positions are funded by the NIH.Contact me directly regarding predoctoral positions.The advertisement and link for submitting an application for the postdoctoral position can be found here by searching for job #18643: https://www.cu.edu/cu-careers
May 28th 2020
Wolfgang Bergmeier: The Bergmeier lab at UNC Chapel Hill is looking for a postdoc candidate interested in platelet and megakaryocyte biology. Please find details in the attached flyer. Please also check out our homepage (http://bergmeierlab.web.unc.edu/) and contact us at bergmeie@email.unc.edu if you are interested.https://www.dropbox.com/s/uygmndxr5erebfh/Postdoc_Bergmeier%20lab%205-20.pdf?dl=0
May 19th 2020
Michael Bruckman: Haima Therapeutics will be looking for 1 FT postdoc, a 1/2 time postdoc, and a FT scientist in the coming months to support the commercialization of our primary product, SynthoPlate. Haima Therapeutics is a small pre-clinical stage biotechnology company located in Cleveland, OH focused on developing bio-inspired therapies for the treatment of bleeding and other blood-related pathologies. We have developed a platelet inspired novel, nanoparticle-based synthetic hemostatic technology, called SynthoPlate, that can staunch bleeding by binding to the site of injury and amplifying your body’s natural clotting mechanisms.
Haima is seeking to hire a highly-motivated Scientist to support fast-paced research and development of its SynthoPlate technology. This person will be responsible for planning drug development experiments, and carrying out NIH, NSF, and DoD relevant projects using biochemistry, molecular biology and polymer science techniques. We are looking for individuals with experience in hemostasis, thrombosis, inflammation, or cell signaling that have worked with various animal models. Additional experience with nanotechnologies, performing large animal studies, writing grants, and managing a team of researchers is a plus. We are seeking individuals with a PhD in biology, chemistry, medicine, or related engineering or medicine majors. Please respond to Michael Bruckman at mbruckman@haimatherapeutics.com if you are interested in a position. The technology was invented by Anirban Sen Gupta (CWRU) with active and future collaborations (from his lab and Haima) with Matthew Neal (UPMC), Wolfgang Bergmeier (UNC), Allan Doctor (University of Maryland), KaloCyte, and Jim Bynum and Adam Meledeo (Institute of Surgical Research).
May 13th 2020
Sol Schulman: NIH funded position available for a motivated postdoctoral fellow to join the Schulman lab (https://hemostasis.bidmc.org/people/sol-schulman-md-phd/) in the Division of Hemostasis and Thrombosis at Beth Israel Deaconess Medical Center. Our lab combines functional genomics, human and rodent genetics, cell biology, and protein biochemistry to dissect the initiation of blood coagulation with a focus on the tissue factor pathway. We are situated in the heart of the Longwood medical area and well integrated into the research environment at Harvard Medical School, enabling immediate access (no Zoom required!) to vast educational opportunities, technical resources, and collaborators. Please contact sschulm1@bidmc.harvard.edu if you may be interested or would like additional information.
10th May 2020
Christian Kastrup: We will have a postdoctoral position at the University of British Columbia in Vancouver, Canada starting September 1st for a molecular biologist with expertise in platelet biology and/or gene therapy. The postdoctoral fellow will be co-supervised by Christian Kastrup and Eric Jan. The research is in collaboration with Pieter Cullis, Dana Devine, Acuitas Therapeutics, the NanoMedicines Innovation Network, and Canadian and US military partners. Vancouver and the University of British Columbia is a wonderful place to live and continue to grow your career.
Please contact me at ckastrup@msl.ubc.ca for more information.
kastruplab.msl.ubc.ca
ubcjanlab.com
liposomes.ca/members/cullis
pathology.ubc.ca/faculty/dana-devine
acuitastx.com
nanomedicines.ca
Macky Neal: The Neal lab (in collaboration with Dr. Melanie Scott at the University of Pittsburgh) has an immediate opening for a post-doc. We are looking for a highly self-motivated individual who is also team-oriented and possesses excellent interpersonal and problem-solving skills. Our labs are part of the research group in the Department of Surgery at the University of Pittsburgh School of Medicine. The successful applicant will be responsible for projects associated with several NIH-funded studies investigating mechanisms of innate immunity in models of trauma, sepsis and acute lung injury associated with sickle cell disease. The primary focus of the work is on mechanisms of activation of inflammasome pathways and signaling, with a particular focus on platelet inflammatory responses, mechanisms of liver and lung damage, hypoxia/reoxygenation injury, and thrombosis and coagulation.
For more information: http://www.surgery.pitt.edu/research/labs/general-surgery-and-vascular-labs/lab-pis/hit3s-research-group-neal-lab or contact me at nealm2@upmc.edu
May 6th 2020
Robert Signer: The Signer Lab is hiring Postdocs! Our curious and creative team at UCSD investigates how the proteostasis network is uniquely configured to promote stem cell function and longevity, and encompasses new therapeutic targets in cancer. Learn more at signerlab.com!
Jordan Shavit: NIH funded pre- and postdoctoral positions are available in my laboratory. We study the genetics of human blood clotting disorders using zebrafish, have developed models of coagulation factor deficiency through genome editing with TALENs and CRISPR, and are currently evaluating these models using next generation sequencing and proteomic technologies. We are in the midst of sensitized mutagenesis and high throughput chemical suppressor screens on mutants with pathologic bleeding and clotting phenotypes in order to identify genetic modifiers and novel molecules with the potential to improve the diagnostic and therapeutic tools available for treatment of affected patients. See our website for a link to the full description: https://www.shavitlab.org/opportunities/ or contact me directly.
Leo Wang: For those interested in CAR T cell signaling and proteomics, or the proteomics of benign and malignant hematopoietic stem and progenitor cells, we are also hiring postdocs/students/RAs. www.leowanglab.org or email directly! (leo.wang at coh dot org)
Joseph Aslan: We are always looking for postdocs (and techs and students) interested in platelets and signaling. Right now, we have some funding specifically in areas of signaling and proteomics of platelet function in inflammation and thrombosis – as well as studying “off target” effects of kinase inhibiting drugs on platelet signaling and function. Please reach out anytime if you are interested and want to talk. Joe Aslan – aslanj@ohsu.edu
May 5th 2020
Jonas Jutzi: Hi everyone. Northeastern University bioinformatic people (mostly co-op) are looking to work for molecular biologists. Please let me know if you look for bioinformatical support in your large-scale experiments using the following tools and are willing (and able) to hire a bioinformatics. Northeastern Data Analytics students have a range of experiences but their skill sets generally includes knowledge/use of the following: R, Python, SQL, MATLAB, Java, Google Analytics, Tableau, PowerBI, Spark, Keras, SAS, PyTorch.
Blood and Bone Seminar 